ABSTRACT Colistin is a last-line antibiotic which acts by causing membrane permeabilization in Gram-negative bacteria.However, its clinical value has been limited by its toxicity and the emergence of resistant organisms.In this study, we showed that econazole and colistin can act synergistically to produce a strong antimicrobial effect sufficient f
Human mesenchymal stem cells modulate the immune response and are good candidates for cell therapy in neuroinflammatory brain disorders affecting both adult and premature USB Port infants.Recent evidence indicates that through their secretome, mesenchymal stem cells direct microglia, brain-resident immune cells, toward pro-regenerative functions, b
Optimizing the aircraft equipment usage scheme of different units according to their task intensity has great significance in improving aircraft reliability and health management.This paper studied the modeling and solving methods of the rotation and echelon usage problems of aircraft equipment measured by dual-life indexes, one of which Pin Cushio
Additive manufacturing, particularly the laser powder bed fusion (LPBF) technique, has ushered in a new era of intricate metallic component fabrication, leveraging the exceptional performance of the Ti6Al4V alloy.However, the intricate mechanical behavior of additively manufactured Ti6Al4V, particularly its anisotropic attributes stemming from non-
BACKGROUND: MicroRNA (miRNA) are negative regulators of gene expression, capable of exerting pronounced influences upon the translation and stability of mRNA.They are potential regulators of normal mammary gland development and of the maintenance of mammary epithelial progenitor cells.This study was undertaken to determine the role of miR-30b on th